Cabergoline for men & women: Dostinex (Know Your Medicine)

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Depending on your prolactinoma, your symptoms and your situation, you may need no treatment at all, or there may be alternatives such as oestrogen or testosterone treatment. If you are not able to tolerate treatment with cabergoline, or if it is not effective in your case, there are similar medications that can be considered, or other treatment options including pituitary surgery. Your endocrinologist will discuss the options with you. Other information Cabergoline oral tablet can interact with other medications, vitamins, or herbs you may be taking. An interaction is when a substance changes the way a drug works. This can be harmful or prevent the drug from working well.

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What to do if you miss a dose: Take your dose as soon as you remember. If you remember just a few hours before your next scheduled dose, take only one dose. Never try to catch up by taking two doses at once. This could result in dangerous side effects. HFEA. 2015. Getting started: your guide to fertility treatment. Human Fertilisation & Embryology Authority. www.hfea.gov.uk Opens a new window [Accessed October 2016] Your endocrinologist will measure the levels of prolactin in blood tests. They may also repeat your pituitary MRI scan once you have been treated for a while. To reduce the risk of developing the rare side-effects of cabergoline treatment, your endocrinologist will usually recommend the lowest effective dose. Some patients go into remission after a couple of years of treatment and the cabergoline can be stopped: blood tests and scans will enable your specialist to monitor for any recurrence. What about pregnancy? Cabergoline is a long-acting medicine, which only needs to be taken once or twice a week. Your specialist will recommend the appropriate dose for you. Common side-effects of cabergoline

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Prolactin levels. Your doctor will do blood tests to measure the amount of prolactin in your body. This will help your doctor decide if you still need treatment with this drug. If you miss doses or don’t take the drug on schedule: Your medication may not work as well or may stop working completely. For this drug to work well, a certain amount needs to be in your body at all times.

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When you have too much prolactin in your body it’s called hyperprolactinemia. Too much prolactin affects the hormones of your menstrual cycle, including Oestrogen, progesterone and follicle-stimulating hormone (FSH). This causes problems with ovulation and makes it difficult to fall pregnant. Studies have found that about 70 percent of women will start to ovulate when Cabergoline is consumed. You may find that any side effects you experience are strongest at the beginning of your treatment. However, they should subside or disappear as your body adjusts to the drug (Allen 2014a,b). Taking your medication with meals, or just after a meal, may help, particularly if you feel nauseous after you take your tablets (Allen 2014a,b). Call your doctor right away if you have serious side effects. Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. Serious side effects and their symptoms can include the following. A prescription for this medication is refillable. You should not need a new prescription for this medication to be refilled. Your doctor will write the number of refills authorized on your prescription. Travel

For seniors: The kidneys and liver of older adults may not work as well as they used to. This can cause your body to process drugs more slowly. As a result, more of a drug stays in your body for a longer time. This raises your risk of side effects. NCCWCH. 2013. Fertility: assessment and treatment for people with fertility problems. National Collaborating Centre for Women's and Children's Health, NICE Clinical Guideline. www.nice.org.uk Opens a new window [Accessed October 2016]